Table 2.

Characteristics of females as of May 15, 2020. Univariate and multivariate logistic regression analyses for increasing risk of Covid-19.

	Cases SARS-CoV-2 positive		Controls SARS-CoV-2 Negative		Total		uOR (95% CI)a	pb	aOR (95% CI)c	p
	n = 5083	%	n = 10,769	%	n = 15,852	%
Median age (IQR) in years, range	48 (37–58), 0–113		42 (32–52), 0–102		44 (34–54), 0–113			<.0001
Age group (years)
0-29	519	10.2	2077	19.3	2596	16.4	1		1
30-52	2720	53.5	6008	55.8	8728	55.1	1.16 (1.13–1.19)	<.0001	2.05 (1.46–2.89)	<.0001
53 +	1844	36.3	2684	24.9	4528	28.6	1.34 (1.30–1.39)	<.0001	2.55 (1.80–3.58)	<.0001
Hospitalized	1883	37.0	2050	19.0	3933	24.8	2.50 (2.32–2.69)	<.0001	NS
Outpatient	3200	63.0	8719	81.0	11,919	75.2	1
Contact with COVID-19
Yes	1465	49.4	3483	50.2	4948	50.0	0.96 (0.88–1.05)	0.45	1.42 (1.13–1.8)	0.0025
No	1500	50.6	3452	49.8	4952	50.0	1		1
Smoking history
Yes	289	5.7	891	8.3	1180	7.5	0.68 (0.58–0.76)	<.0001	0.49 (0.31–0.78)	<.0023
No	4788	94.3	9868	91.7	14,656	92.5	1		1
Pneumonia	1414	27.8	1292	12.0	2706	17.1	2.82 (2.59–3.07)	<.0001	1.56 (1.25–1.93)	<.0001
No-pneumonia	3668	72.2	9476	88.0	13,144	82.9	1		1
Obesity	1967	38.8	3582	33.3	5549	35.0	1.26 (1.18–1.36)	<.0001	5.55 (4.09–7.51)	<.0001
Non-obesity	3107	61.2	7181	66.7	10,288	65.0	1		1
Diabetes	914	18.0	1309	12.2	2223	14.0	1.58 (1.44–1.73)	<.0001	3.91 (2.98–5.29)	<.0001
No-diabetes	4161	82.0	9446	87.8	13,607	86.0	1		1
Hypertension	1158	22.8	2099	19.5	3257	20.6	1.21 (1.12–1.32)	<.0001	3.25 (3.36–4.48)	<.0001
No-hypertension	3920	77.2	8660	80.5	12,580	79.4	1		1
Cardiovascular disease	78	1.5	280	2.6	358	2.3	0.58 (0.45–0.75)	<.0001	NS
No-cardiovascular diseas	4999	98.5	10,476	97.4	15,475	97.7	1
COPD	68	1.3	222	2.1	290	1.8	0.64 (0.49–0.84)	0.0015	NS
No-COPD	5009	98.7	10,536	97.9	15,545	98.2	1
Asthma	350	6.9	1488	13.8	1838	11.6	0.46 (0.40–0.52)	<.0001	NS
Non-asthma	4725	93.1	9276	86.2	14,001	88.4	1
Immunosuppression	95	1.9	402	3.7	497	3.1	0.49 (0.39–0.61)	<.0001	NS
Non-inmmunesuppression	4977	98.1	10,353	96.3	15,330	96.9	1
Chronic renal failure	64	1.3	136	1.3	200	1.3	0.99 (0.74–1.34)	0.99	2.25 (1.69–3.01)	0.0011
No-chronic renal failure	5010	98.7	10,626	98.7	15,636	98.7	1		1
Pregnant	63	1.2	174	1.6	237	1.5	0.76 (0.57–1.02)	0.07	-NS
No-pregnant	5005	98.8	10,567	98.4	15,572	98.5	1
Tracheally intubated	151	8.0	133	6.5	284	7.2	1.25 (0.98–1.59)	0.06	NS
Non-intubated	1731	92.0	1912	93.5	3643	92.8	1
In ICU	176	9.4	155	7.6	331	8.4	1.25 (1.0–1.57)	0.04	NS
Non-ICU	1705	90.6	1890	92.4	3595	91.6	1
Death	424	8.3	220	2.0	644	4.1	4.3 (3.69–5.15)	<.0001	2.25 (1.69–3.01)	<.0001
Alive	4659	91.7	10,549	98.0	15,208	95.9	1		1

SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; IQR: interquartile range; COPD: chronic obstructive pulmonary disease; ICU: intensive care unit; NS: not selected by the backward elimination procedure in the multivariable logistic regression analysis with a significance level set at 0.2; NI: not included in the multivariate analysis; Covid-19:coronavirus disease.

^aUnadjusted odds ratio and 95% confidence interval.

^bDifferences between cases and controls. Totals may not add up due to missing data.

^cAdjusted odds ratio and 95% confidence interval.