Table A2.
Performance of the risk scores at different cutoff points.
| Cutoff Point * | High Risk n (%) |
Sensitivity (95%CI) |
Specificity (95%CI) |
PPV (95%CI) |
NPV (95%CI) |
LR+ (95%CI) |
LR- (95%CI) |
|---|---|---|---|---|---|---|---|
| 3 | 152 (40.1) |
0.81 (0.71–0.89) |
0.71 (0.66–0.76) |
0.44 (0.36–0.52) |
0.93 (0.89–0.96) |
2.81 (2.28–3.46) |
0.27 (0.17–0.42) |
| >3.5 | 133 (35.1) |
0.77 (0.67–0.86) |
0.77 (0.71–0.81) |
0.48 (0.39–0.57) |
0.92 (0.88–0.95) |
3.31 (2.61–4.19) |
0.30 (0.20–0.45) |
| >4 | 114 (30.1) |
0.72 (0.61–0.82) |
0.82 (77–86) |
0.53 (43–62) |
0.91 (87–94) |
3.96 (3.01–5.22) |
0.34 (0.24–0.48) |
| >4.5 | 76 (20.1) |
0.53 (0.42–0.64) |
0.89 (0.85–0.92) |
0.58 (0.46–0.69) |
0.87 (0.83–0.91) |
4.90 (3.34–7.21) |
0.53 (0.42–0.66) |
| >5 | 66 (17.4) |
0.49 (0.38–0.61) |
0.92 (0.88–0.94) |
0.62 (0.49–0.74) |
0.87 (0.82–0.90) |
5.85 (3.79–9.02) |
0.55 (0.45–0.69) |
| >5.5 | 42 (11.1) |
0.37 (0.27–0.49) |
0.96 (0.93–0.98) |
0.74 (0.58–0.86) |
0.85 (0.80–0.88) |
10.05 (5.28–19.12) |
0.65 (0.55–0.77) |
* Sum of the risk score. PPV: Positive Predictive Value; NPV: Negative Predictive Value; LR+: Positive Likelihood Ratio; LR-: Negative Likelihood Ratio; CI: Confidence Interval.