Figure 2.

Binarization and skeletonization of en face optical coherence tomography angiography (OCTA) of original, averaged, and denoised images. (A–C), OCTA images. (D–F), Binarized images. (G–I), Skeletonized images. A, D, G, Original images. B, E, H, Averaged images. C, F, I, Denoised images. The binarized image in D shows multiple noise in the foveal avascular zone (FAZ) and burr-like shape at the edges of the vessels (indicated by an arrow), suggesting that background noise could have been falsely included as blood flow. The binarized images of the averaged and denoised images in E and F show less noise and smoother vessels than the original image in D. The skeletonized image in G shows disconnected lines and dots in nonvascular areas. Compared with the original image in G, the skeletonized images of the averaged and denoised images in H and I show annealing lines that reduce the disconnected lines and dots.