Figure 5.

Effect of Acute IL-6 and Insulin Treatment on Neuronal Cell Glucose Uptake. SH-SY5Y cells were treated with 100 nM insulin, 10 ng/mL, or 20 ng/mL IL-6 for 30 min followed by glucose uptake measurements. Acute insulin and IL-6 (20 ng/mL) treatment significantly increase glucose uptake (CON, n = 4; INS, n = 4; IL-6 (10), n = 6; IL-6 (20), n = 6). Data are presented as mean ± SE of 6 independent experiments, expressed as percent of control * p ≤ 0.05, as determined using a one-way ANOVA followed by Fisher’s LSD post hoc analysis.