Figure 2.

Coronary arteries produce high levels of CYP-derived oxylipins. Figures show detectable CYP epoxygenase (a) EPOX-AA, (b) EPOX-LA, (c) EPOX-DHA/EPA and (d) CYP-OH products released by pig aorta (black bars) and coronary artery (grey bars). Oxylipins accumulated in 24 h serum-free organ culture were measured by LC–MS/MS and expressed as pg/mg of wet tissue weight. Data represents organ culture from n = 3–4 separate animals. Data represents organ culture from n = 3–4 separate animals. * indicates p < 0.05 between Aorta and CA.