3D	three dimensional;
AO	adverse outcome;
BSA	bovine serum albumin;
CAS	chemical abstracts service;
CNS	central nervous system;
Ctrl	control;
D	day;
DNT	developmental neurotoxicity;
EC	effective concentration;
ER	endoplasmic reticulum;
FBS	fetal bovine serum;
HE	Hematoxylin-Eosin;
HTS	high-throughput screening;
hiPSC	human induced pluripotent stem cell;
ICC	immunocytochemistry;
iPSC	induced pluripotent stem cell;
NA	numeric aperture;
NAM	new approach method;
NEAA	non-essential amino acids;
NIM	neural induction media;
NMM	neural maintenance media;
NPC	neural progenitor cell;
NSC	neural stem cell;
O/N	overnight;
PBMC	peripheral blood mononuclear cells;
PBS	phosphate buffer saline;
PCR	polymerase chain reaction;
PFA	Paraformaldehyde;
POL/L	Poly-l-ornithine and Laminin;
PSC	pluripotent stem cell;
RT	room temperature;
rTdT	recombinant terminal deoxynucleotidyl transferase;
RT-PCR	reverse transcription polymerase chain reaction;
TEM	transmission electron microscopy;
TUNEL	terminal deoxynucleotidyl transferase dUTP nick end labeling.