Table 11.

Overview on the extraction experiments by Mroczek et al. to investigate the influence of extraction techniques using different solvents for different times at different temperatures on the extraction yield of PAs for the example of Symphytum. The results correspond to the sum of PAs quantified by UV-Vis [152] (1st, first extraction; 2nd, second extraction).

	Technique	Sample (g)	Volume (mL)	Time (h)	Temperature (°C)	Solvent	Result (ppm)
1	Maceration	1	100	6	Room temperature	Methanol	802
2	Maceration	1	100	12	Room temperature	Methanol	695
3	Maceration	1	100	18	Room temperature	Methanol	854
4	Maceration	1	100	12	50–60	Methanol	1081
5	Reflux	1	100	2 (1st)	Boiling Point	Methanol	1251
6	Reflux	1	100	2 (2nd)	Boiling Point	Methanol	155
7	Percolation	5	500	2	Room temperature	Methanol	1051
8	Percolation	2	200	2	Room temperature	Methanol	640
9	Maceration	1	100	10	Room temperature	1% methanolic solution of tartaric acid	1024
10	Reflux	1	100	1	Boiling Point	1% methanolic solution of tartaric acid	1092
11	Reflux	1	100	2	Boiling Point	1% methanolic solution of tartaric acid	1301
12	Reflux	1	100	4	Boiling Point	1% methanolic solution of tartaric acid	1155
13	Sonication	1	100	0.5	Room temperature	1% methanolic solution of tartaric acid	436
14	Maceration	1	100	18	Room temperature	Ethanol 95%	363
15	Reflux	1	100	4	Boiling Point	Ethanol 95%	1258
16	Maceration	1	100	6	Room temperature	2.5% HCl	498
17	Reflux	1	100	0.5	Boiling Point	2.5% HCl	304
18	Reflux	1	100	2	Boiling Point	2.5% HCl	214
19	Maceration	1	100	1	Room temperature	Chlorofom/MeOH/Ammonia	229
20	Sonication	1	100	0.5	Room temperature	5% Acetic Acid	650
21	Reflux	1	100	2	Boiling Point	1% methanolic solution of ascorbic acid	163