Table 14.

Overview on experiments by Lebada et al. to investigate extraction parameter on the yield of Senkirkine from Tussilago quantified by CE-UV [118].

	Technique	Sample (g)	Volume (mL)	Time (min)	Temperature (°C)	Solvent	Result (ppm)
1	Flask	15	1500	30	Room Temperature	Water	2.9
2	Reflux	15	1500	15	Boiling Point	Water	9.3
3	Reflux	10	1000	15	Boiling Point	Water acidified with citric acid	8.0
4	Reflux	10	300	15	Boiling Point	Methanol/Water (50/50) acidified with citric acid	8.0
5	Reflux	10	600	15	Boiling Point	Methanol/Water (50/50) acidified with citric acid	11.2
6	Reflux	10	1000	15	Boiling Point	Methanol/Water (50/50) acidified with citric acid	11.0
7	Reflux	10	1000	120	Boiling Point	Methanol/Water (50/50) acidified with citric acid	9.2
8	Reflux	10	300	15	Boiling Point	Methanol/Water (50/50) alkalized with ammonia	8.9
9	Reflux	10	1000	15	Boiling Point	Methanol/Water (50/50) alkalized with ammonia	8.4
10	Soxhlet	10	500	2880	Boiling Point	Methanol	2.5
11	Reflux	10	1000	15	Boiling Point	Methanol alkalized with ammonia	5.0