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. 2020 May 7;12(5):516. doi: 10.3390/v12050516

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Genomic analyses of putative recombinant sapoviruses present limited evidence of recombination at the RdRp-VP1 boundaries. (a) Site-by-site nucleotide similarity analyses of four strains (GI.1/HK7 [MN794208], GII.4/T003 [MN794218], GIV.1/Ehime1107 [DQ058829] [6], and GIII.3/p2 [KX688107] [9]) that presented differences in the phylogenetic clustering when using RdRp- or VP1-encoding regions. (b) Inter-genotype/genogroup nucleotide substitution differences among the two genomic regions; RdRp and VP1. The VP1-encoding region presented a higher number of substitutions between the different genotypes/genogroups. Note the lack of both parental strains for the putative recombinant strains.