Table 1.
1 GO _BP Analysis for Host Genes of 2DE circRNAs | p-Value | 1 GO_BP Analysis of 2 DE mRNAs | p-Value |
---|---|---|---|
Negative regulation of cytokine-mediated signaling pathway | 6.1 × 10−2 | Nuclear division | 1.6 × 10−5 |
Negative regulation of response to cytokine stimulus | 6.3 × 10−2 | Meiotic cell cycle | 2.8 × 10−5 |
Lipid localization | 7.1 × 10−2 | Organelle fission | 2.9 × 10−5 |
Anatomical structure homeostasis | 7.4 × 10−2 | Regulation of reproductive process | 8.3 × 10−5 |
Activation of cysteine-type endopeptidase activity involved in apoptotic process | 8.3 × 10−2 | Meiotic cell cycle process | 1.4 × 10−4 |
Fatty acid transport | 1.0 × 10−1 | Meiotic nuclear division | 3.0 × 10−4 |
Cardiac muscle cell differentiation | 1.1 × 10−1 | Cell cycle process | 3.5 × 10−4 |
Regulation of cytokine-mediated signaling pathway | 1.1 × 10−1 | Regulation of nuclear division | 5.2 × 10−4 |
Regulation of response to cytokine stimulus | 1.2 × 10−1 | Mitotic nuclear division | 5.9 × 10−4 |
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 1.2 × 10−1 | Regulation of cell cycle process | 6.0 × 10−4 |
Regulation of cell proliferation | 1.2 × 10−1 | Cell cycle | 1.1 × 10−3 |
Positive regulation of cysteine-type endopeptidase activity | 1.3 × 10−1 | Regulation of cell cycle | 1.5 × 10−3 |
Positive regulation of hydrolase activity | 1.3 × 10−1 | Regulation of cell growth | 1.7 × 10−3 |
Cell aging | 1.3 × 10−1 | Negative regulation of reproductive process | 2.2 × 10–3 |
Intracellular signal transduction | 1.4 × 10−1 | Mitotic cell cycle process | 2.2 × 10−3 |
Positive regulation of endopeptidase activity | 1.4 × 10−1 | Regulation of growth | 2.5 × 10−3 |
Regulation of signal transduction | 1.4 × 10−1 | Endoderm formation | 2.7 × 10−3 |
Positive regulation of peptidase activity | 1.4 × 10−1 | Positive regulation of cell cycle process | 2.9 × 10−3 |
Cardiocyte differentiation | 1.5 × 10−1 | Positive regulation of cytokinesis | 3.2 × 10−3 |
Organophosphate catabolic process | 1.5 × 10−1 | Endoderm development | 3.4 × 10−3 |
1 GO_BP: biological processing terms from gene ontology; 2 DE: differentially expressed.