Table 2.
Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis for all differentially expressed transcripts in all groups.
| DE 1 circRNA Host Genes KEGG 2 Analysis | p-Value | DE 1 mRNA KEGG 2 Analysis | p-Value |
|---|---|---|---|
| VEGF signaling pathway | 1.1 × 10−1 | Oocyte meiosis | 2.3 × 10−3 |
| PPAR signaling pathway | 1.2 × 10−1 | ECM–receptor interaction | 7.8 × 10−3 |
| TGF-beta signaling pathway | 1.4 × 10−1 | Focal adhesion | 1.4 × 10−2 |
| GnRH signaling pathway | 1.5 × 10−1 | Regulation of actin cytoskeleton | 2.3 × 10−2 |
| Oocyte meiosis | 1.7 × 10−1 | Hedgehog signaling pathway | 4.8 × 10−2 |
| Vascular smooth muscle contraction | 1.9 × 10−1 | Cell cycle | 7.0 × 10−2 |
| Ubiquitin-mediated proteolysis | 2.3 × 10−1 | Progesterone-mediated oocyte maturation | 7.6 × 10−2 |
| MAPK signaling pathway | 3.6 × 10−1 | Cardiac muscle contraction | 8.8 × 10−2 |
| Metabolic pathways | 6.9 × 10−1 | Neuroactive ligand–receptor interaction | 9.6 × 10−2 |
| Basal transcription factors | 1.8 × 10−1 | ||
| Glutathione metabolism | 1.9 × 10−1 | ||
| FoxO signaling pathway | 2.0 × 10−1 | ||
| Adrenergic signaling in cardiomyocytes | 2.0 × 10−1 | ||
| Cytokine–cytokine receptor interaction | 2.1 × 10−1 | ||
| p53 signaling pathway | 2.2 × 10−1 | ||
| Phagosome | 2.3 × 10−1 | ||
| Cell adhesion molecules (CAMs) | 2.6 × 10−1 | ||
| Jak-STAT signaling pathway | 3.1 × 10−1 | ||
| TGF-beta signaling pathway | 3.4 × 10−1 | ||
| Vascular smooth muscle contraction | 3.7 × 10−1 |
1 DE: differentially expressed; 2 KEGG: Kyoto Encyclopedia of Genes and Genomes.