Table 3.

Protein content or transcriptional activation for regulatory or anti-inflammatory/antioxidative systems in monocytes from patients with CKD compared to healthy individuals.

System	Function	Comparison to Healthy Controls	Quote
SOD1	Superoxide dismutase 1, antioxidative	Protein content low, transcription rate high	[39]
SOD2	Superoxide dismutase 2, antioxidative	Reduced protein content CKD3/4, normal CKD5D; enhanced transcriptional activation all CKD	[40]
Rhodanese	Regulation of mitochondrial reactive oxygen species production	Protein content and transcription low	[41]
Hsp72	Heat shock protein 72, protein folding and degradation, cellular damage protection	Protein content and transcription low	[42]
SOCS3	Suppressor of cytokine signaling, modulates intracellular signaling after cytokine-receptor interaction	Enhanced transcription	[43]
Lp-PLA2	Lipoprotein-associated Phospholipase A2, platelet activation, pro-atherogenic	Enhanced transcription	[44]
ACE ACE2 AT1-R AT2-R	Angiotensin converting enzyme Angiotensin converting enzyme type 2 Angiotensin II receptor Type 1 Angiotensin II receptor Type 2	Enhanced transcription Reduced transcription Enhanced transcription Normal transcription	[45]