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. 2020 May 13;9(5):1211. doi: 10.3390/cells9051211

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Normalized median fluorescence intensities (MFI) of the surface protein profiles of the plasma-derived sEVs from healthy blood donors (HBD), patients with antiphospholipid syndrome (APS) and aPL-neg patients with idiopathic thrombosis (aPL-neg IT). The nonparametric Kruskal–Wallis test with Dunn’s multiple comparison adjustment was used. Grouped surface protein profiles are shown indicating the cell of origin (upper panel) and cell activation status/functional properties of the sEVs (lower panel).