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. 2020 May 9;9(5):1397. doi: 10.3390/jcm9051397

Figure 1.

Figure 1

Possible mechanisms of dysregulated inflammatory response during chronic granulomatous disease (CGD). Abbreviations: IL-8, Interleukin–8; IL-1β, Interleukin–1β; Nrf2, nuclear factor erythroid 2-related factor 2; PGD2, prostaglandin D2; TGF-β, transforming growth factor beta; mtROS, mitochondrial reactive oxygen species; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells; TNF alfa, tumor necrosis factor alfa.