Table 2.
Basic clinical data for patients with chronic granulomatous disease (CGD).
| No. | Sex (Male/Female) | Age, Years | Genetic Mutation | Age at CDG Diagnosis, Years | Clinical Manifestations Leading to Diagnosis of CGD |
|---|---|---|---|---|---|
| 1 | M | 25 | CYBB | 6 | Skin abscess |
| 2 | M | 25 | CYBB | 5 | Brain abscess; liver abscess; rectal abscess; pneumonitis; myocarditis; erythema nodosum |
| 3 | M | 4 | CYBB | 2 | Perianal abscesses |
| 4 | M | 26 | CYBB | 1 | Lymph nodes and skin abscesses; several with pneumonitis |
| 5 | M | 28 | CYBB | 10 | Pneumonia |
| 6 | M | 39 | NCF1 | 13 | Liver abscess |
| 7 | F | 24 | NCF1 | 17 | Liver abscesses; perianal abscesses |
| 8 | F | 9 | NCF1 | 7 | Lymphadenitis; |
| 9 | F | 13 | NCF1 | 11 | Recurrent pneumonia |
| 10 | F | 6 | NCF1 | 5 | Lymphadenitis; rectal abscess |
| 11 | M | 2 | NCF1 | 1 | Pneumonia; pulmonary aspergillosis |
| 12 | M | 36 | NCF1 | 34 | Syphilis; skin abscesses; staphylococcal abscess of the brain and lungs |
| 13 | F | 12 | NCF1 | 10 | Mulch pneumonia |
| 14 | M | 24 | NCF1 | 20 | Liver abscess |
| 15 | M | 26 | NCF1 | 6 | Liver abscess; tuberculosis of the lymph nodes |
CYBB, gp91 phox; NCF1, gp47phox.