a.u. |
arbitrary units |
CA4 |
combretastatin A-4 |
CRBN |
cereblon |
CUL4A |
cullin 4A |
DCC |
dicyclohexyl carbodiimide |
DDB1 |
damage specific DNA binding protein |
DMP |
Dess-Martin periodinane |
DMSO |
dimethyl sulfoxide |
HATU |
hexafluorophosphate azabenzotriazole tetramethyl uronium |
hTert |
human telomerase reverse transcriptase |
IC |
inhibitory concentration |
KRAS |
Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
MMAE |
monomethyl auristatin E |
MOA |
mechanism of action |
P |
polymerized |
PDB |
protein data bank |
PROTAC |
proteolysis-targeting chimera |
RBX1 |
ring box 1 |
RPE1 |
retinal pigment epithelium 1 |
S |
soluble |
SAR |
structure-activity relationship |
SEM |
standard error of the mean |
STMN |
stathmin |
TFA |
trifluoroacetic acid |
TLC |
thin-layer chromatography |
TUBA |
α-tubulin |
TUBB |
β-tubulin |
UbcH5A |
ubiquitin-conjugated enzyme E2D1 |
Ub |
ubiquitin |
UPS |
ubiquitin-proteasome system |