Table S3. Association between the clinic characteristics and the prognosis of the lung cancer patients.
| Variables | Southern samples | Eastern samples | Merged samples | MST (month) | log-rank P value | Crude HR (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case, N | Death, N (%) | Case, N | Death, N (%) | Case, N | Death, N (%) | ||||||
| Total | 110 | 88 (80%) | 53 | 45 (84.9) | 163 | 133 (81.6) | |||||
| Age | |||||||||||
| <60 | 64 | 50 (78.1) | 34 | 27 (79.4) | 98 | 77 (78.6) | 24.5 | 1.00 (Ref.) | |||
| ≥60 | 46 | 38 (82.6) | 19 | 18 (94.7) | 65 | 56 (86.2) | 22.5 | 0.575 | 1.10 (0.78–1.56) | ||
| Sex | |||||||||||
| Female | 38 | 29 (76.3) | 16 | 13 (81.3) | 54 | 42 (77.8) | 26.8 | 1.00 (Ref.) | |||
| Male | 72 | 59 (81.9) | 37 | 32 (86.5) | 109 | 91 (83.5) | 22.2 | 0.345 | 0.84 (0.58–1.21) | ||
| Family history of cancer | |||||||||||
| No | 100 | 79 (79.0) | 45 | 38 (84.4) | 145 | 117 (80.7) | 24.4 | 1.00 (Ref.) | |||
| Yes | 10 | 9 (90.0) | 8 | 7 (87.5) | 18 | 16 (88.9) | 19.0 | 0.353 | 1.28 (0.76–2.17) | ||
| Smoking | |||||||||||
| No | 44 | 32 (72.7) | 20 | 15 (75.0) | 64 | 47 (73.5) | 29.4 | 1.00 (Ref.) | |||
| Yes | 66 | 56 (84.9) | 33 | 30 (90.9) | 99 | 86 (86.9) | 20.0 | 0.015 | 1.56 (1.09–2.22) | ||
| Drinking | |||||||||||
| No | 83 | 67 (80.7) | 40 | 34 (85.0) | 123 | 101 (82.1) | 24.2 | 1.00 (Ref.) | |||
| Yes | 27 | 21 (77.8) | 13 | 11 (84.6) | 40 | 32 (80.0) | 21.3 | 0.600 | 1.11 (0.75–1.66) | ||
| Stage | |||||||||||
| I + II | 42 | 31 (73.8) | 13 | 10 (76.9) | 55 | 41 (74.5) | 32.2 | 1.00 (Ref.) | |||
| III + IV | 68 | 57 (83.8) | 40 | 35 (87.5) | 108 | 92 (85.2) | 19.1 | 0.004 | 1.73 (1.19–2.52) | ||
| Histological types | |||||||||||
| Adenocarcinoma | 56 | 44 (78.6) | 20 | 16 (80.0) | 76 | 60 (78.9) | 29.0 | 1.00 (Ref.) | |||
| Squamous cell carcinoma | 30 | 25 (83.3) | 18 | 20 (90.0) | 48 | 45 (93.8) | 19.7 | 0.114 | 1.38 (0.93–2.04) | ||
| Large cell carcinoma | 2 | 2 (100.0) | 3 | 3 (100.0) | 5 | 5 (100.0) | 12.6 | 0.070 | 2.34 (0.93–5.86) | ||
| Small cell lung cancer | 11 | 9 (81.8) | 4 | 2 (50.0) | 15 | 11 (73.3) | 12.9 | 0.095 | 1.76 (0.91–3.40) | ||
| Other carcinomasa | 11 | 8 (72.7) | 6 | 6 (100.0) | 17 | 14 (93.3) | 15.6 | 0.083 | 1.68 (0.93–3.00) | ||
a, mixed-cell or undifferentiated carcinoma. MST, median survival time; HR, hazard ratio; ref, reference.