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. 2020 May;8(9):594. doi: 10.21037/atm-20-3554

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A 79-year-old female was diagnosed with severe COVID-19. After seven days treatment, her symptoms relieved. (A,B,C) However, the chest CT showed that the area of infection increased rapidly. The quantitative analysis result showed several zone 4 area interval density in her infectious area. Her symptoms deteriorated the next day, and the gas arterial blood gas analysis showed ARDS. (D,E,F) After 12 days’ treatment, another Quantitative CT analysis result showed the area of Zone4 decrease while the area of zone 8 increase (the zone 8 density mainly distributed in fibrous tissue area, black arrow in D), which could indicate the disease was on the mend. COVID-19, coronavirus disease 2019; CT, computed tomography.