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. 2020 May 11;11(5):534. doi: 10.3390/genes11050534

Figure 2.

Figure 2

Lorenz curves of coverage uniformity for reconstructed mtDNA genomes. The cumulative fraction of sequence reads against the cumulative fraction of genome covered is shown for each amplification protocol (eWGA, DOP-PCR, MALBAC and MDA) followed by WGS in HT-29 cells, the unamplified bulk of HT-29 and scATACseq data. The diagonal line represents the ideal perfect uniform coverage. The plot was generated using the Lc function in R package ineq.