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. 2020 May 19;12(5):560. doi: 10.3390/v12050560

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Annotated feature importance plots for the 20 most important features in Convolutional Neural Network classifiers. Horizontal axes are amino acid positions; vertical axes are feature importance (measured as change in 1-AUC). Abbreviations: FPV = fosamprenavir; ATV = atazanavir; IDV = indinavir; LPV = lopinavir; NFV = nelfinavir; SQV = saquinavir; TPV = tipranavir; DRV = darunavir; 3TC = lamivudine; ABC = abacavir; AZT = azidothymidine; D4T = stavudine; DDI = didanosine; TDF = tenofovir disoproxil fumarate; EFV = efavirenz; NVP = nevirapine; ETR = etravirine; RPV = rilpivirine; PI = protease inhibitor; NRTI = nucleotide reverse transcriptase inhibitor; NNRTI = non-nucleotide reverse transcriptase inhibitor.