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. 2020 May 15;9(5):1227. doi: 10.3390/cells9051227

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Activation and differentiation markers in spleen-derived T CD4+ cells co-cultured with APCs. The expression of activation and differentiation markers in spleen-derived T CD4+ cells after co-culture with hepatic APCs in CCl₄ and BDL animals administered or not with norfloxacin. Percentage of T CD4+ cells expressing CD25 and CD71 in CCl₄ model (A) and BDL model (B). Percentage of T CD4+ cells expressing Foxp3 (Treg), IFNg (Th1), IL-4 (Th2), and IL-17 (Th17) in CCl₄ model (C) and BDL model (D). Mean values ± standard deviations are represented from at least 5 animals per group. * p < 0.01 compared with norfloxacin-untreated animals.