Table 2.
Comparisons of clinical conditions and laboratory data between survivors and non-survivors.
| Characteristics | Total (n = 210) |
Survivor (n = 157) |
Non-Survivor (n = 53) |
p-Value |
|---|---|---|---|---|
| Predisposing conditions, yes | ||||
| Prior stay in ICU | 129 (61.4) | 89 (56.7) | 40 (75.5) | 0.015 |
| Recent surgery | 44 (21.0) | 31 (19.7) | 13 (24.5) | 0.459 |
| Ventilator use | 149 (71.0) | 107 (68.2) | 42 (79.2) | 0.124 |
| Multiple injuries | 4 (1.9) | 4 (2.5) | 0(0.0) | 0.574 |
| Immunocompromised status, yes | 66 (31.4) | 42 (26.8) | 24 (45.3) | 0.012 |
| Invasive device use, yes | ||||
| Central venous catheter | 169 (80.5) | 121 (77.1) | 48 (90.6) | 0.032 |
| Foley catheter | 178 (85.2) | 130 (83.3) | 48 (90.6) | 0.201 |
| Endotracheal tube | 163 (77.6) | 121 (77.1) | 42 (79.2) | 0.743 |
| Port-A catheter | 6 (2.9) | 4 (2.5) | 2 (3.8) | 0.644 |
| Cerebrospinal shunt | 5 (2.4) | 4 (2.5) | 1 (1.9) | >0.999 |
| Pleural catheter | 36 (17.1) | 24 (15.3) | 12 (22.6) | 0.219 |
| Pancreaticobiliary catheter | 8 (3.8) | 5 (3.2) | 3 (5.7) | 0.419 |
| Laboratory test on Day 0 | ||||
| Leukocytosis (>10,000 mm/µL) | 135 (64.3) | 102(65.0) | 33 (62.3) | 0.722 |
| RDW (%) | 16.4 ± 2.5 | 15.7 ± 2.7 | 16.8 ± 4.0 | 0.221 |
| Delta-neutrophil (%) | 6.0 ± 20.1 | 1.7 ± 3.1 | 3.0 ± 6.0 | 0.727 |
| Thrombocytopenia, yes (/µL) | 81 (38.6) | 47 (29.9) | 34 (64.2) | <0.001 |
| Severe thrombocytopenia, yes (/µL) | 26 (12.4) | 13 (8.3) | 13 (24.5) | 0.002 |
| Hypoalbuminemia, yes (g/dL) | 98 (46.9) | 64 (41.0) | 34 (64.2) | 0.004 |
| CRP/albumin ratio | 26.6 ± 29.3 | 22.6 ± 26.9 | 50.4 ± 37.2 | <0.001 |
| Renal insufficiency, yes (%) | 60 (28.6) | 47 (29.9) | 13 (24.5) | 0.451 |
| Laboratory test on Day 7 | ||||
| Leukocytosis (>10,000/µL) | 123 (67.6) | 101 (69.2) | 22 (61.1) | 0.354 |
| RDW (%) | 16.7 ± 2.3 | 16.2 ± 2.4 | 16.6 ± 2.3 | 0.210 |
| Delta-neutrophil (%) | 3.7 ± 7.7 | 5.1 ± 19.7 | 6.3 ± 13.2 | 0.072 |
| Thrombocytopenia, yes (/µL) | 61 (33.5) | 38 (26.0) | 23 (63.9) | <0.001 |
| Severe thrombocytopenia, yes (/µL) | 21 (11.5) | 11 (7.5) | 10 (27.8) | 0.001 |
| Hypoalbuminemia, yes (g/dL) | 81(45.0) | 61 (42.1) | 20 (57.1) | 0.108 |
| CRP/albumin ratio | 24.3 ± 25.0 | 18.2 ± 18.9 | 45.7 ± 30.1 | <0.001 |
| Renal insufficiency, yes (%) | 52 (28.6) | 43 (29.5) | 9 (25.0) | 0.596 |
ICU, Intensive Care Unit; RDW, Red Cell Distribution Width; CRP, C-reactive protein of acquisition. Renal insufficiency was defined as a calculated glomerular filtration rate (GFR) of less than 60 mL per minute/1.73 m2. Thrombocytopenia and severe thrombocytopenia were defined as a platelet count of less than 100,000 and 50,000 per µL, respectively. Hypoalbuminemia was defined as a low blood level of albumin of less than 2.8 g per dL. Continuous variables are shown as the mean ± standard deviation (SD) and categorical variables, as numbers (percentage).