Table 1. The characteristics of the 381 patients grouped by SII, NLR, PLR and PNI.

Variables	Cases (number, %)		SII (number)		P value	NLR (number)		P value	PLR (number)		P value	PNI (number)		P value
	381 (100)		<682.98	≥682.98		<2.69	≥2.69		<118.74	≥118.74		<49.95	≥49.27
Gender					0.895			0.436			0.903			0.101
Male	294 (77.2)		202	92		194	100		142	152		113	181
Female	87 (22.8)		61	26		62	25		43	44		25	62
Age (years)					0.377			0.231			1			0.001
≤60	194 (50.9)		138	56		136	58		94	100		54	140
>60	187 (49.1)		125	62		120	67		91	96		84	103
Smoking					0.401			0.123			0.504			0.049
Ever	266 (69.8)		180	86		172	94		126	140		105	161
Never	115 (30.2)		83	32		84	31		59	56		33	82
Drinking					0.119			0.066			0.588			0.013
Ever	253 (66.4)		169	84		162	91		120	133		103	35
Never	128 (33.6)		94	34		94	34		65	63		150	93
Tumor length					0.001			0.001			0.001			0.002
≤4	221 (58.0)		174	47		166	55		124	97		65	156
>4	160 (42.0)		89	71		90	70		61	99		73	87
Tumor type					0.136			0.001			0.027			0.291
LCNEC	143 (37.5)		90	53		82	61		60	83		57	86
SCLC	181 (47.5)		132	49		126	55		101	80		65	116
AC	57 (15.0)		41	16		48	9		24	33		16	41
T stage					0.001			0			0.001			0.001
T1	128 (33.6)		113	15		106	22		81	47		33	95
T2	150 (39.4)		96	54		91	59		72	78		59	91
T3	61 (16.0)		35	26		38	23		22	39		20	41
T4	42 (11.0)		19	23		21	21		10	32		26	16
N stage					0.077			0.123			0.745			0.896
N0	190 (49.9)		140	50		137	53		96	94		71	119
N1	86 (22.6)		59	27		53	33		40	46		30	56
N2	105 (27.6)		64	41		66	39		49	56		37	68
M stage					1			0.6			0.359			0.623
M0	377 (99.0)		260	117		254	123		182	195		136	241
M1	4 (1.0)		3	1		2	2		3	1		2	2
TNM stage					0.001			0.007			0.038			0.135
I	142 (37.3)		111	31		107	35		81	61		48	94
II	93 (24.4)		68	25		66	27		42	51		27	66
III	142 (37.3)		81	61		81	61		59	83		61	81
IV	4 (1.0)		3	1		2	2		3	1		2	2
Operation time (min)					0.293			0.367			0.918			0.127
<180	294 (77.2)		207	87		201	93		138	156		100	194
≥180	87(22.8)		56	31		55	32		47	40		38	49
Intraoperative blood loss (mL)					0.314			0.061			0.273			0.519
<200	216 (56.7)		154	62		154	62		104	112		75	141
≥200	165 (43.3)		109	56		102	63		81	84		63	102
Treatment					0.419			0.363			0.669			0.579
Surgery only	247 (64.8)		174	73		170	77		122	125		87	160
Surgery with adjuvant therapy	134 (35.2)		89	45		86	48		63	71		51	83

NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; SII, systemic immune-inflammation index; PNI, prognostic nutritional index; LCNEC, large cell neuroendocrine carcinoma; SCLC, small cell lung cancer; AC, atypical carcinoid