Table 6. GRADE evidence profile of MERS studies.
| No. of studies | Certainty assessment | No. of patients | Effect value (95% CI) | Quality of the evidence (GRADE) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Sample | Intervention | Control | ||||
| Mortality | |||||||||||
| CS [1] | Not serious | Not serious | Not serious | Not serious | None | 309 | 151 | 158 | RR 1.29 (1.09 to 1.52) | ⨁⨁◯◯ (low) | |
| ICU mortality | |||||||||||
| CS [1] | Not serious | Not serious | Not serious | Not serious | None | 309 | 151 | 158 | RR 1.34 (1.14 to 1.58) | ⨁⨁◯◯ (low) | |
| Hospital mortality | |||||||||||
| CS [1] | Not serious | Not serious | Not serious | Not serious | None | 309 | 151 | 158 | RR 1.33 (1.14 to 1.56) | ⨁⨁◯◯ (low) | |
| Virus clearance | |||||||||||
| CS [1] | Not serious | Not serious | Not serious | Not serious | None | 203 | 99 | 104 | RR 1.15 (0.77 to 1.72) | ⨁⨁◯◯ (low) | |
| Length of hospital stay | |||||||||||
| CS [1] | Not serious | Not serious | Not serious | Serious3 | None | 203 | 99 | 104 | WMD 6.30 (2.36 to 10.24) | ⨁◯◯◯ (very low) | |
3, downgrade one level: Sample size is less than optimal information sample (OIS). RR, risk ratio; CI, confidence interval; WMD, weighted mean difference; CS, cohort study.