Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May;8(10):647. doi: 10.21037/atm-20-3768

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

BC inhibits AGE-induced autophagy. H9c2 cells were pre-treated with BC (40 µM) and then stimulated with AGEs (200 µg/mL) for 24 h. (A) The protein levels of beclin 1, p62, and LC3 were detected by Western blot. (B,C,D) Semi-quantitative analysis of the relative level of beclin 1, p62, and LC3. (E) Representative images of intracellular LC3 redistribution (green spots) in H9c2 cells under different conditions. (F) The quantification of the number of LC3 puncta. Each experiment was performed in triplicate. *, P<0.05 vs. control group; ^#, P<0.05 vs. AGE-induced group. BC, beta-carotene; AGEs, advanced glycation end products; LC3, microtubule-associated protein 1 light chain 3.