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. 2020 May;8(10):646. doi: 10.21037/atm-20-3079

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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ALKBH5 was upregulated in RCC tissues and cell lines and acted as a prognostic factor for RCC patients. (A) ALKBH5 mRNA expression in 26 pairs of RCC tissues and matched adjacent tissues. (B) ALKBH5 protein expression in RCC tissues and matched adjacent tissue. Eight cases are shown as examples. The fold change of ALKBH5 is shown below each lane. (C,D) ALKBH5 mRNA and protein expression in RCC cell lines and normal epithelium cells of renal tubule HK2. (E) Kaplan-Meier survival curves depicting overall survival of patients with RCC based on ALKBH5 expression conditions. Data are presented as mean ± SD. *. P<0.05. RCC, renal cell carcinoma.