Table 1. Clinical characteristics of the mothers with influenza or SARS-CoV-2 and their infants.
Clinical characteristics | Chen 2020 (2) | Zhang 2020 (16) | Lei 2020 (17) | Dong 2020 (18) | Wang 2020 (19) | Cantey 2013 (20) | |
---|---|---|---|---|---|---|---|
Period of observation | 2020 | 2020 | 2020 | 2020 | 2020 | 2003 to 2005 | 2009 to 2010 |
Study site | Wuhan, China | Haikou, China | Wuhan, China | Wuhan, China | Wuhan, China | Dallas, USA | |
Mothers | |||||||
Number of mothers | 9 | 1 | 4 | 1 | 1 | 23 | 19 |
Median age(years) | 30 | – | 32 | 29 | 34 | 26 | 26 |
Type of infection | |||||||
Influenza | 1 | 0 | 0 | 0 | 0 | 23 | 19 |
SARS-CoV-2 | 9 | 1 | 4 | 1 | 1 | 0 | 0 |
Mode of delivery | |||||||
Vaginal | 0 | 1 | 1 | 0 | 0 | 14 | 14 |
Cesarean section | 9 | 0 | 3 | 1 | 1 | 9 | 5 |
Infants | |||||||
Number of infants | 9 | 1 | 4 | 1 | 1 | 23 | 19 |
Girl | – | 1 | – | 1 | 0 | 9 | 10 |
Boy | – | 0 | – | 0 | 1 | 14 | 9 |
Median birth weight (g) | 2,789 | – | 2,803 | 3,120 | 3,205 | 3,123 | 3,333 |
Median gestational age (weeks) | 37 | – | 36 | 38 | 40 | 38 | 40 |
Age | Neonate | 3 months 19 days | Neonate | Neonate | Neonate | Neonate | Neonate |
Median APGAR score | |||||||
1 min | 9 | – | 9 | 9 | 8 | 8 | 9 |
5 min | 10 | – | 10 | 10 | 9 | 9 | 9 |
Breast milk RT-PCR | |||||||
Positive | 0 | 0 | 0 | 0 | 0 | – | - |
Negative | 6 | 1 | 4 | 1 | 1 | – | - |
Breastfeeding | |||||||
Wearing a surgical mask | – | 0 | – | – | – | 0 | 19 |
Hygiene measure before close contact with infant | – | 0 | – | – | – | 23 | 19 |
Signs of infection | 0 | 1 | 0 | 0 | 0 | 0 | 0* |
Throat swab RT-PCR | |||||||
Positive | 0 | 1 | 0 | 0 | 0 | – | 0 |
Negative | 6 | 0 | 4 | 1 | 1 | – | 1# |
–, not reported; *, two infants lost to follow-up; #, one infant with fever (source not identified); influenza rapid test and polymerase chain reaction test negative.