Table 3. Radiological assessment of patients in the three CTC subgroups.
| Response | Negative-CTC (<11 FU/3 mL) | Low CTC level (11–16 FU/3 mL) | High CTC level (>16 FU/3 mL) | P |
|---|---|---|---|---|
| Radiological response, n (%) | – | |||
| PR | 7 (18.4) | 2 (6.3) | 9 (32.1) | |
| SD | 24 (63.2) | 15 (46.9) | 13 (46.4) | |
| PD | 5 (13.2) | 4 (12.5) | 0 (0) | |
| No assessment | 5 (13.2) | 11 (34.4) | 6 (21.4) | |
| Clinical response rate, % | ||||
| ORR | 21.2 | 9.5 | 40.9 | 0.0485 |
| DCR | 93.9 | 81.0 | 100.0 | 0.0599 |
CTC, circulating tumor cell; FU, folate receptor unit; PR, partial response; SD, stable disease; PD, disease progression; ORR, objective response rate; DCR, disease control rate.