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. 2020 May;8(10):644. doi: 10.21037/atm-20-3371

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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PPI prevented cardiac dysfunction. (A) After 24 h of reperfusion, myocardial histology was detected by HE staining; representative images were taken under 200× magnification. (B) Left ventricular ejection fraction (LVEF), left ventricular wall thickness (LVWT) and left ventricular end-systolic volume (LVESV) were assessed by echocardiography. Data are presented as the mean ± SD (n=10). *, P<0.05 vs. control group, ^#, P<0.05 vs. I/R group. All independent experiments were repeated at least three times. PPI, polyphyllin I; I/R, ischemia/reperfusion.