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. 2020 May 13;9(5):1456. doi: 10.3390/jcm9051456

Figure 5.

Figure 5

Kaplan–Meier 5-year survival estimates. (A) Comparison of all patients who underwent targeted PAH treatment for either congenital heart disease-associated pulmonary hypertension (CHD treated, total) or incident idiopathic PAH. The 5-year Kaplan–Meier survival estimate was 76% for PAH due to CHD and 54% for idiopathic PAH (p < 0.001). (B) Comparison of subgroups of patients with CHD and PAH under targeted PAH medication: (1) CHD-treated, total (green); (2) Eisenmenger-patients-treated (EM treated; purple); (3) non-Eisenmenger-PAH-patients (Non-EM treated; blue). The overall 5-year survival estimate was 76%, compared with 78% for the Eisenmenger patients, and 77% for the non-Eisenmenger-PAH-patients (p = 0.384). (C) Comparison of subgroups of patients with Eisenmenger syndrome due to complex or simple CHD. The 5-year Kaplan–Meier survival estimate was 81% for Eisenmenger syndrome caused by simple CHD and 64% for Eisenmenger syndrome due to complex CHD (p = 0.063). Kaplan–Meier survival estimates (top) and number of cases still under observation (bottom) are shown in tabular form. Abbreviations: CHD, congenital heart disease; non-EM, non-Eisenmenger-PAH-patients; PAH, pulmonary arterial hypertension.