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. 2020 Apr 30;9(5):1117. doi: 10.3390/cells9051117

Table 1.

Model parameters determined by Markov chain Monte Carlo (MCMC) simulation of human melanoma.

Cell Line Type Parameters Values Unit How to Obtain the Parameter’s Values
HX34 cell line α 0 0.263 ± 0.016 Gy−1 MCMC with ref. [45] (60Co γ-ray data)
β 0 0.047 ± 0.005 Gy−2 MCMC with ref. [45] (60Co γ-ray data)
(a + c) 8.857 ± 2.175 * h−1 MCMC with ref. [45] (60Co γ-ray data)
M8 cell line
(primary melanoma)
α 0 0.612 ± 0.130 Gy−1 MCMC with ref. [39] (60Co γ-ray data)
β 0 0.066 ± 0.020 Gy−2 MCMC with ref. [39] (60Co γ-ray data)
(a + c) 8.769 ± 2.128 h−1 Update with ref. [39] and the (a + c) value *
Mel-J cell line
(metastatic melanoma)
α 0 0.002 ± 0.047 Gy−1 MCMC with ref. [39] (60Co γ-ray data)
β 0 0.050 ± 0.009 Gy−2 MCMC with ref. [39] (60Co γ-ray data)
(a + c) 8.916 ± 2.126 h−1 Update with ref. [39] and the (a + c) value *

*: The (a + c) value used for update is that determined from the MCMC and experimental data of HX34 cells.