Figure 6.

Hepatic genes and proteins. (A–F): Hepatic expression of genes involved in cholesterol metabolism and their alteration upon HFD + atorvastatin treatment in CONV (n = 15) and ABS (n = 19) mice. (G–J): Hepatic protein expression of sterol regulatory element-binding protein 2 (Srebp2) and ldl receptor (Ldlr) gene expression by atorvastatin in ABS (n = 12) mice as compared to CONV (n = 12) mice. The protein levels of srebp2 and ldlr were further evaluated by Western Blot (B). Error bars indicate SEM. * = p < 0.05, ** = p < 0.01; *** = p < 0.001.