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. 2020 May 17;9(5):1239. doi: 10.3390/cells9051239

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The activity of sphingolipid metabolizing enzymes in brains of female HAB and LAB rats. The activity of acid and neutral sphingomyelinases (ASM in (a), NSM in (b)) as well as of acid and neutral ceramidases (AC in (c), NC in (d)) was analyzed in the frontal cortex (FC), dorsal striatum (DS), lateral septum (LS), ventral striatum (VS), amygdala (AM), dorsal hippocampus (DH), thalamus (TH), hypothalamus (HY), ventral hippocampus (VH), dorsal mesencephalon (DM), ventral mesencephalon (VM) and cerebellum (CE). HAB rats showed a significant increase in the activity of these enzymes compared with LAB rats. Data represent individual data points with means ± SEM. * p < 0.05.