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. 2020 May 12;9(5):1430. doi: 10.3390/jcm9051430

Figure 5.

Figure 5

Correlations between NRP1 expression and gene markers of Treg, TAM, and M1 and M2 macrophages in STAD and LUAD. Infiltration level of NRP1 expression with various gene markers of Treg cells, TAM, M1 macrophages, and M2 macrophages was confirmed using TIMER. FOXP3, CCR8, and TGFβ1 were used as markers for Treg cells, and CCL2, CD68, and IL10 were used as markers for TAM. Moreover, NOS2, IRF5, and COX2 were used as markers for M1 macrophages, and CD163, VSIG4, and MS4A4A were used as markers for M2 macrophages. NRP1 expression was positively correlated with the expression of various gene markers for Treg cells, TAM, and M2 macrophages in STAD. However, the correlation of NRP1 expression with various gene markers in LUAD was weaker than in STAD. Correlation constants and P-values are listed in Table 1.