Table 2.
Correlation analysis between NRP1 expression and genes markers of Treg cells, TAM, M1 macrophages, and M2 macrophages using GEPIA 2.
| Cell Type | Gene Markers | STAD | LUAD | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Tumor | Normal | Tumor | Normal | ||||||
| R | P | R | P | R | P | R | P | ||
| Treg | FOXP3 | 0.35 | *** | −0.36 | 0.03 | 0.21 | *** | 0.31 | 0.019 |
| CCR8 | 0.5 | *** | −0.22 | 0.19 | 0.33 | *** | 0.25 | 0.059 | |
| STAT5B | 0.62 | *** | 0.87 | *** | 0.37 | *** | 0.84 | *** | |
| TGF β (TGFB1) | 0.59 | *** | 0.17 | 0.33 | 0.43 | *** | 0.43 | ** | |
| TAM | CCL2 | 0.48 | *** | 0.41 | 0.013 | 0.23 | *** | 0.12 | 0.36 |
| CD68 | 0.46 | *** | −0.32 | 0.057 | 0.29 | *** | 0.11 | 0.42 | |
| IL10 | 0.58 | *** | 0.2 | 0.25 | 0.21 | *** | 0.024 | 0.86 | |
| M1 Macrophage | INOS (NOS2) | 0.017 | 0.74 | 0.28 | 0.1 | 0.19 | *** | 0.62 | *** |
| IRF5 | 0.59 | *** | 0.67 | *** | 0.29 | *** | −0.19 | 0.15 | |
| COX2 (PTGS2) | 0.33 | *** | 0.77 | *** | 0.2 | *** | 0.21 | 0.11 | |
| M2 Macrophage | CD163 | 0.59 | *** | 0.67 | *** | 0.29 | *** | −0.19 | 0.15 |
| VSIG4 | 0.6 | *** | 0.64 | *** | 0.28 | *** | −0.2 | 0.12 | |
| MS4A4A | 0.64 | *** | 0.61 | *** | 0.31 | *** | −0.22 | 0.099 | |
** P < 0.001; *** P < 0.0001.