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. 2020 May 22;9(5):1582. doi: 10.3390/jcm9051582

Table 1.

Comparison of clinical prediction models for recurrent venous thromboembolism.

Score Variables Inclusion Criteria Definition of Unprovoked VTE Findings—Risk of Recurrent VTE
DASH [11] Abnormal D-dimer after AC
Age ≤ 50
Gender
Hormone therapy
First unprovoked VTE Absence of:
Surgery
Trauma
Active cancer
Immobility
Pregnancy and puerperium
Included:
Hormone therapy
Thrombophilic blood abnormality (if no other VTE risks)
Annualised recurrence risk:
Score ≤ 1:3.1%
Score > 1:9.3%
HERDOO2 [8] Gender
Signs of post-thrombotic syndrome
Abnormal D-dimer during on AC
BMI ≥ 30
Age ≥ 65
First unprovoked VTE after 5–12 months of AC Absence of:
Major surgery within 3 months
Malignancy within 5 years
Immobilisation for ≥ 3 days
Leg fracture or plaster cast
Included:
Travel-related
Exogenous oestrogen
Minor immobilisation
Minor surgery
Annualised recurrence risk:
Low-risk (0 or 1 factor) females: 1.6%
High-risk (≥ 2 factors) females: 14.1% per year
Males (no low-risk group identified): 13.7%
Vienna [9] Gender
VTE location
D-dimer after ceasing AC
First unprovoked VTE after at least 3 months of AC Absence of:
Major surgery
Major trauma
Pregnancy
Female hormone intake
Hereditary thrombophilia
Malignancy
Included:
Immobility
Continuous HR based on nomogram

BMI: body mass index; HR: hazard ratio; AC: anticoagulation; VTE: venous thromboembolism.