Table 2.
Adenosine receptors binding parameters in lymphocytes from patients with ischemic stroke in comparison with healthy subjects. Data are expressed as the mean ± SEM. Differences were considered significant at a value of ** p < 0.01 vs healthy controls.
| A1ARs | A2AARs | A2BARs | A3ARs | |
|---|---|---|---|---|
| Healthy subjects (n = 50) | ||||
| KD (nM) | 1.74 ± 0.11 | 1.48 ± 0.10 | 2.11 ± 0.20 | 1.87 ± 0.14 |
| Bmax (fmol/mg protein) | 52 ± 4 | 63 ± 5 | 53 ± 5 | 76 ± 8 |
| Ischemic stroke patients (n = 50) | ||||
| KD (nM) | 1.58 ± 0.12 | 0.97 ± 0.04** | 2.34 ± 0.16 | 1.91 ± 0.11 |
| Bmax (fmol/mg protein) | 45 ± 3 | 168 ± 14** | 58 ± 6 | 87 ± 9 |