Table 1.
Summarized or averaged demographic data as well as clinical and laboratory parameters for all patients and control individuals.
| Parameter | CTRL I (101–115) i | CTRL II (151–165) j | FGR I (301–315) i | FGR II (351–365) j | SGA I (201–215) i | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean | 95% CI | Min. | Max. | n | Mean | 95% CI | Min. | Max. | n | Mean | 95% CI | Min. | Max. | n | Mean | 95% CI | Min. | Max. | n | Mean | 95% CI | Min. | Max. | |
| Mat. Age (years) a | 15 | 29.4 | 26.5–32.3 | 21.5 | 39.2 | 15 | 30.5 | 27.7–33.3 | 24.2 | 39.0 | 15 | 28.1 | 25.1-31.1 | 22.0 | 41.8 | 15 | 30.4 | 26.8-34.0 | 19.1 | 41.5 | 15 | 28.9 | 24.9–32.8 | 17.6 | 40.2 |
| Mat. BMI, (kg/m2) b | 15 | 22.8 | 21.7–23.9 | 19.5 | 26.9 | 15 | 23.3 | 20.4–26.2 | 17.6 | 35.7 | 15 | 22.2 | 20.6–23.9 | 18.0 | 28.9 | 15 | 24.2 | 22.4–26.1 | 19.9 | 31.9 | 15 | 22.4 | 20.6–24.3 | 16.2 | 28.1 |
| Primiparity, (%) | 15 | 100.0 | n.a. | n.a. | n.a. | 15 | 80.0 | n.a. | n.a. | n.a. | 15 | 93.3 | n.a. | n.a. | n.a. | 15 | 86.7 | n.a. | n.a. | n.a. | 15 | 86.7 | n.a. | n.a. | n.a. |
| Smoking Status, (%) | 15 | 20.0 | n.a. | n.a. | n.a. | 15 | 20.0 | n.a. | n.a. | n.a. | 15 | 46.7 | n.a. | n.a. | n.a. | 15 | 26.7 | n.a. | n.a. | n.a. | 15 | 26.7 | n.a. | n.a. | n.a. |
| Systolic bp, (mmHg) c | 15 | 115.6 | 109.2–122.0 | 99 | 135 | 15 | 116.2 | 121.1–120.3 | 106 | 129 | 15 | 120.4 | 113.6–127.2 | 96 | 139 | 15 | 130.9 | 118.6–143.1 | 83 | 162 | 15 | 117.5 | 108.9–126.2 | 84 | 146 |
| Diastolic bp, (mmHg) c | 15 | 68.9 | 63.1–74.6 | 54 | 87 | 15 | 64.9 | 60.5–69.4 | 53 | 81 | 15 | 69.1 | 63.6–74.5 | 52 | 82 | 15 | 77.3 | 68.2–86.3 | 52 | 101 | 15 | 66.3 | 60.2–72.3 | 45 | 84 |
| ga at sample, (weeks) d | 15 | 29.4 | 28.3–30.5 | 25.7 | 32.6 | 15 | 32.4 | 29.8–35.0 | 25 | 39.3 | 15 | 29.6 | 28.3–30.9 | 25.4 | 33.9 | 15 | 32.3 | 29.7–34.9 | 24 | 40.4 | 15 | 31.0 | 29.3–32.7 | 22.9 | 34.6 |
| ga at delivery, (weeks) d | 15 | 39.6 | 38.9–40.3 | 37.4 | 41.6 | 15 | 32.8 | 30.2–35.3 | 25 | 39.3 | 15 | 30.5 | 29.2–31.8 | 25.9 | 34.1 | 15 | 33.0 | 30.5–35.5 | 26.7 | 40.4 | 15 | 38.1 | 37.4–38.8 | 36.1 | 40.7 |
| Δt (days) e | 15 | 71.3 | 62.7–79.8 | 50 | 105 | 15 | 2.7 | 0.01–5.3 | 0 | 18 | 15 | 6.3 | 2.1–10.6 | 0 | 31 | 15 | 4.7 | 0.95–8.4 | 0 | 19 | 15 | 49.9 | 37.1–62.8 | 22 | 105 |
| C-section, (%) f | 15 | 20.0 | n.a. | n.a. | n.a. | 15 | 86.7 | n.a. | n.a. | n.a. | 15 | 100.0 | n.a. | n.a. | n.a. | 15 | 100.0 | n.a. | n.a. | n.a. | 15 | 66.7 | n.a. | n.a. | n.a. |
| Fetal Birth Weight, (g) | 15 | 3399 | 3232–3565 | 2960 | 3765 | 15 | 2129 | 1584–2673 | 740 | 3895 | 15 | 1015 | 845–1185 | 495 | 1525 | 15 | 1383 | 1005–1761 | 490 | 2665 | 15 | 2465 | 2299–2630 | 1950 | 2780 |
| fbw Percentile g | 15 | 47.1 | 37.5–56.8 | 14 | 70 | 15 | 50.7 | 40.8–60.5 | 25 | 85 | 15 | 5.2 | 3.8–6.6 | 2 | 9 | 15 | 4.0 | 2.5–5.5 | 1 | 9 | 15 | 4.5 | 3.2–5.7 | 1 | 9 |
| Female, (%) h | 15 | 60.0 | n.a. | n.a. | n.a. | 15 | 53.3 | n.a. | n.a. | n.a. | 15 | 40.0 | n.a. | n.a. | n.a. | 15 | 53.3 | n.a. | n.a. | n.a. | 15 | 46.7 | n.a. | n.a. | n.a. |
(a) mat: maternal age in years determined at the beginning of hospitalization (time point of blood sampling); n.a.: not applicable; (b) pre pregnancy BMI; (c) blood pressure; (d) gestational age; (e) time interval between sample collection and delivery; (f) c: caesarea, mode of delivery; (g) fbw: fetal birth weight; (h) fetal gender; (i) this study; (j) from [7].