Table 5.
Neither control with solvent nor the combination of 5.3 µg/kg, 17 µg/kg and 54 µg/kg STX with 44 µg/kg TTX altered b.w. or accumulated weight change of mice during the 28 day treatment period.
| Group | Day 0 | Day 7 | Day 14 | Day 21 | Day 28 |
|---|---|---|---|---|---|
| Control | (n = 4) | (n = 4) | (n = 4) | (n = 4) | (n = 4) |
| Body weight (g) | 21.4 ± 1.2 | 23.1 ± 1.4 | 24.6 ± 1.2 | 25.9 ± 1.5 | 25.1 ± 1.3 |
| Cumulative b.w. (g) | 0.0 | 1.7 ± 1.0 | 3.2 ± 0.8 | 2.9 ± 0.5 | 0.5 ± 0.5 |
| 5.3 µg/kg STX + 44 µg/kg TTX | (n = 4) | (n = 4) | (n = 4) | (n = 4) | (n = 3) |
| Body weight (g) | 21.3 ± 0.6 | 24.0 ± 1.2 | 24.5 ± 1.2 | 25.6 ± 1.4 | 24.6 ± 2.4 |
| Cumulative b.w. (g) | 0.0 | 2.7 ± 1.0 | 3.2 ± 0.9 | 1.8 ± 0.7 | −0.6 ± 1.2 |
| 17 µg/kg STX + 44 µg/kg TTX | (n = 5) | (n = 5) | (n = 5) | (n = 5) | (n = 5) |
| Body weight (g) | 21.0 ± 1.5 | 22.5 ± 0.9 | 24.1 ± 0.8 | 24.9 ± 0.9 | 22.7 ± 1.0 |
| Cumulative b.w. (g) | 0.0 | 1.5 ± 0.8 | 3.1 ± 1.0 | 2.5 ± 0.3 | −1.4 ± 0.4 |
| 54 µg/kg STX + 44 µg/kg TTX | (n = 5) | (n = 4) | (n = 3) | (n = 3) | (n = 3) |
| Body weight (g) | 22.5 ± 0.3 | 23.4 ± 0.9 | 23.6 ± 0.7 | 24.0 ± 0.7 | 24.4 ± 0.9 |
| Cumulative b.w. (g) | 0.0 | 0.8 ± 0.7 | 1.2 ± 0.2 | 1.5 ± 0.2 | 0.7 ± 0.3 |
The number of animals for each condition is indicated in parenthesis. Values are expressed as mean ± SEM.