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. 2020 May 25;9(5):1321. doi: 10.3390/cells9051321

Figure 2.

Figure 2

Immunoblot measurement of MAP1LC3B turnover and its dynamics. (A) Pictorial representation of the autophagic flux process. Baf A1 inhibits the autophagy process by blocking the autophagosome–lysosomal fusion. (B–E) Effect of a test compound on MAP1LC3-II expression. Without the use of Baf A1, it would be unpredictable to assess whether the compound is increasing the autophagosome synthesis or inhibiting the autophagosome degradation. Modified from [59]. See abbreviations in the abbreviations section.