Table 3.

Next-generation sequencing terms.

Next-Generation Sequencing Techniques
Whole-genome sequencing (WGS)	Single-nucleotide resolution of all genome bases
Whole-exome sequencing (WES)	Single-nucleotide resolution of protein-codon areas of the genome
Targeted sequencing	Covers limited subsets of candidate genes
RNA sequencing	Sequencing of each RNA transcript
Gene expression profiling	Evaluates the RNA level of a single gene with further functional associations; cell environment as potential bias