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. 2020 Apr 27;11(5):475. doi: 10.3390/genes11050475

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Overview of TC+M-FISH for the detection of chromosomal aberrations (A) Description of the TC+M-FISH approach. (B) Sensitivity of TC+M-FISH in the detection of dicentric chromosomes in cancer patients and those with genetic disorders compared to conventional cytogenetics. (C) Reporting time from the analysis of blood samples from patients, with or without complex karyotypes, using the TC+M-FISH approach compared to conventional cytogenetics (D) The cost (in euros) of the two approaches for the analysis of a simple and complex karyotype, based on the European situation.