Fig. 5.

Effect of resveratrol on mid-chain HETE metabolite formation rate in RL-14 cells. RL-14 cells were treated for 24 h with vehicle, 10 μM Ang II and 10 μM Ang II in combination with (2, 10 or 50 μM resveratrol). 5-, 8-, 9-HETE (a) and 11-, 12-, 15-HETE (b) metabolites were measured using LC–ESI–MS. The results are presented as the mean and SEM (n = 3). Data were analyzed using one-way ANOVA followed by Student–Newman–Keuls as post hoc test. ⁺p < 0.05 significantly different from control group. *p < 0.05 significantly different from Ang II-treated group