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Unfolded protein response (UPR) induction under ER stress caused by thapsigargin (TG) treatment. (A) Morphological changes in the cell population in response to ER stress observed using an optical microscope. (WT, TG treatment for 12 or 24 h). Scale bar: 200 μm (B) Morphological changes in the ER structure under dimethyl sulfoxide (DMSO) or TG treatment conditions; Red line indicates the ER structure in hPSCs. Scale bar: 1 μm.
