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Structural proteins in mono- and quadri-subtype VLPs. (a) Mono-subtype H7N9 VLP with H7, N9 and M1 genes; (b) Mono-subtype chimeric H7N1 VLP with H7, N1, and Gag genes; (c) Quadri-subtype VLPs co-localizing H5, H7, H9 and H10 subtypes along with N1 and Gag within a VLP.
