Figure 6.
Expression of mRNA for NF-κB (A), c-Jun (B), c-Fos (C), TNF-α (D), TNF-R2 (E), IL-6R (F), IL-1β (G), IL-1R1 (H), IL-1R2 (I), IL-1RA (J), SOCS3 (K) and annexin-A1 (L) in esophageal mucosa of rats pretreated i.g. with vehicle or tricarbonyldichlororuthenium (II) dimer (CORM-2, 2.5 mg/kg) and exposed to 4 h of reflux esophagitis (RE). Intact refers to healthy esophageal mucosa not exposed to RE. Results are mean ±SEM of 5 samples per group. Results are expressed as fold change of normalized esophageal mucosal mRNA expressions. Asterisk indicates a significant change as compared with respective values obtained in intact esophageal mucosa, not exposed to RE (p < 0.05). Cross indicates a significant change as compared with the values obtained in the vehicle-pretreated group exposed to RE (p < 0.05).
