Table 2.

Parasporin characteristics.

PS	Bt Strain	Cry Gene	Protoxin (kDa)	Active Toxin (kDa)	Protease Activation	Main Cellular Target	EC50 [µg/mL]	Mechanism Action	Country	Reference
PS1Aa1	A1190	Cry31Aa1	81	15, 56	Trypsin	HeLa	0.12	Apoptosis	Japan	[99]
PS1Aa2	M15	Cry31Aa2	83	55, 70	Trypsin	Jurkat HepG2	0.02 0.02	ND	Canada	[128]
PS1Aa3	B195	Cry31Aa3	81	56	Trypsin	HeLa	14.7	ND	Japan	[116]
PS1Aa4	Bt79-25	Cry31Aa4	81	NP	Proteinase K	ND	ND	ND	Vietnam	[122]
PS1Aa5	Bt92-10	Cry31Aa5	81	NP	Proteinase K	ND	ND	ND	Vietnam	[122]
PS1Aa6	M019, 64-1-94	Cry31Aa6	70	15, 55	Trypsin	HepG2	0.52	ND	Japan, Caribbean	[117,129]
PS1Ab1	B195	Cry31Ab1	82	56	Trypsin	HeLa	14.7	ND	Japan	[116]
PS1Ab2	Bt31-5	Cry31Ab2	82	NP	Proteinase K	ND	ND	ND	Vietnam	[122]
PS1Ac1	Bt87-29	Cry31Ac1	87	NP	Proteinase K	ND	ND	ND	Vietnam	[122]
PS1Ac2	B0462	Cry31Ac2	81	15, 60	Proteinase K	HeLa	2	Apoptosis	Japan	[118]
PS1Ad1	64-1-94, M15, M019	Cry31Ad1	73	14, 59	Trypsin	HepG2	0.52	ND	Caribbean, Canada, Japan	[117,128,129]
PS2Aa1	A1547	Cry46Aa1	37	30	Proteinase K	HepG2	0.023	Pore-forming	Japan, USA	[105]
PS2Aa2	A1470	Cry31Aa2	30	28	Proteinase K	MOLT-4	0.041	ND	Japan	[119]
PS2Ab1	TK-E6	Cry31Ab1	33	29	Proteinase K	Jurkat	0.545ng/ml	ND	Japan	[113]
PS3Aa1	A1462	Cry41Aa1	88	64	Proteinase K	HL60	1.32	ND	Japan	[100]
PS3Ab1	A1462	Cry41Ab1	88	64	Proteinase K	HL60	1.25	ND	Japan	[100]
PS4Aa1	A1470	Cry45Aa1	31	28	Proteinase K	CaCo2	0.124	Pore-forming	Japan	[111]
PS5Aa1	A1100	Cry64Aa1	33	30	Proteinase K	TCS	0.046	ND	Japan	[120]
PS6Aa1	M019, 64-1-94	Cry63Aa1	85	14, 59	Trypsin	HepG2	2.3	ND	Japan, Caribbean	[117,129]

NP- not published. ND- not determined.