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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: J Immunol. 2020 Mar 23;204(9):2514–2522. doi: 10.4049/jimmunol.1901508

Figure 5. IRF8 activates IRF3 for IFN-β production.

Figure 5.

(A,B) Immunoblot analysis of phospho (p)-IRF3, IRF3, p-TBK1, TBK1, p-IKKε, and IKKε in wild-type (WT) or Irf8–/– bone marrow-derived macrophages (BMDMs) infected with E. coli (multiplicity of infection [MOI], 10) and C. rodentium (MOI, 10) for the indicated time. GAPDH was used as an internal control. Data are representative of three experiments.