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. 2020 Jun 12;21:243. doi: 10.1186/s12859-020-03576-5

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Allelic concordance of CTi eQTLs with eQTLs from purified cells. CTi eQTLs show high allelic concordance compared to eQTLs from purified cell subpopulations9. (a) for granulocyte eQTLs (green), CTi eQTLs achieved an allelic concordance of 99% compared to eQTLs from purified neutrophils. Similarly, the allelic concordances were 96 and 99% for CD14+ monocytes and CD4+ T cells, respectively. Except for monocytes, these values are higher than those observed for whole blood eQTLs when comparing to eQTLs from purified subpopulations, as shown in panel (b)