Table 2.
The top 5 KEGG and Reactome pathways related to proteins involved in UBE2I network
| Pathway-term | Description | False discovery rate |
|---|---|---|
| KEGG pathways | ||
| hsa04120 | Ubiquitin mediated proteolysis | 5.25e−08 |
| hsa03013 | RNA transport | 6.03e−08 |
| hsa05418 | Fluid shear stress and atherosclerosis | 1.20e−04 |
| hsa04064 | NF-kappa B signaling pathway | 2.20e−03 |
| hsa04630 | Jak-STAT signaling pathway | 5.00e−03 |
| Reactome pathways | ||
| HSA-2990846 | SUMOylation | 9.18e−14 |
| HSA-3108232 | SUMO E3 ligases SUMOylate target proteins | 2.99e−10 |
| HSA-3108214 | SUMOylation of DNA damage response and repair proteins | 9.43e−08 |
| HSA-3065678 | SUMO is transferred from E1 to E2 (UBE2I, UBC9) | 3.48e−07 |
| HSA-4615885 | SUMOylation of DNA replication proteins | 6.65e−07 |